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1) dukkha (as explained by Samyak Buddha Shakyamuni)
2) neurobiological diseases (does that doesn't contradict science; like Alzheimer)
3) genetical defects (that are proved by science)
(a) Bodhisattva Vincenzi
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Comments
yes... it may be one in this year.
but the next year, it will be a reform of western tought :: Rinascita II
2) should be "those" not "does"